It is very rare that you will ever see or reach a queen termite. She is deep in the termite colony, producing the next generation of termites. Termite colonies have specific roles or castes, such as workers, soldiers, reproductives, etc. This system makes the colony dependent on all the castes for survival. If enough workers are eliminated, then the colony will effectively collapse. Therefore, the most effective treatments target the workers, as they are more numerous and more likely to get into the termiticide.